Studies on the immunosuppressive action of rat seminal plasma.
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Studies on the immunosuppressive action of rat seminal plasma. by David Timothy Shakespeare

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Published by University of Manchester in Manchester .
Written in English


Book details:

Edition Notes

Manchester thesis (M.Sc.), School of Biological Sciences.

ContributionsUniversity of Manchester. School of Biological Sciences.
The Physical Object
Pagination153p.
Number of Pages153
ID Numbers
Open LibraryOL16572425M

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The effect of the immunosuppressive fraction of boar seminal vesicle fluid (ISF) was tested on the manifestation of adjuvant arthritis (AA) in rats. The inhibitory effect of ISF on. been shown to exert immunosuppressive effects. It has been shown that the major protein secreted from rat seminal vesicle has non-species specific immunosuppressive and anti-inflammatory propert 16). However, the effects of human Sg on human lymphocyte functions have not been fully elucidated. In this study we have studied whether Sg has. The immunosuppressive effects of seminal plasma in vivo Published reports on the immunological effects of seminal plasma in vivo are scarce but also reveal immuno- Immunology Today, vol. 5, No. 12, suppressive by: Lord EM, Sensabaugh GF, Stites DP. Immunosuppressive activity of human seminal plasma. I. Inhibition of in vitro lymphocyte activation. J Immunol. May; (5)– Marcus ZH, Freisheim JH, Houk JL, Herman JH, Hess EV. In vitro studies in reproductive immunology. by: 5.

Similarly, bovine seminal ribonuclease presents immunosuppression activity by interfering strongly with the expression of the interleukin‐2 receptor on T cells, and it exerts action through its ability to catalyze the cleavage of RNA (Tamburrini et al, ). Study the roles of these immunosuppressive enzymes in other ruminant SPs could be an Cited by: A study was made of the biosynthesis of choline-con-taining lipids by cell-free extracts of rat seminal vesicle (). It was established that this tissue contained active phosphorylcholine-cytidyl and phos-phorylcholine-glyceryl transferases, which catalyze the synthesis . The usefulness of plasma drug concentration data is based on the concept that pharmacologic response is closely related to drug concentration at the site of action. For certain drugs, studies in patients have provided infor-mation on the plasma concentration range that is safe and effective in treating specific diseases—the therapeu-. Seminal plasma, and not epididymal spermatozoa, have an inhibitory effect on the direct hemolytic plague forming cell response. This was mediated by a direct inhibitory effect on the B cell and not through the generation of suppressor T cells as demonstrated by responses to T-independent and Cited by:

  Site of action of immunosuppressive agents on T cell. Immunosuppression is delivered in two phases A. Induction (started immediately post-transplant, when the risk of rejection is highest) and done with anti-T-lymphocyte–depleting or non-depleting antibodies. B.   Immunosuppressive plasma cells are generated in response to TGFβ, and their functionality depends on the expression of programmed death ligand 1 and interleukin Cited by: Seminal Plasma Infertile Woman Testicular Germ Cell Immunosuppressive Factor Antisperm Antibody These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm : Deborah J. Anderson.   Immunosuppressive drug has one meaning: a drug that lowers the body’s normal immune response. IMMUNOSUPPRESSANT DRUGS: IMMUNOSUPPRESSANT DRUGS I. inhibitors of cytokine (IL-2) production or action: 1) Calcineurin inhibitors Cyclosporine Tacrolimus (FK) 2) Sirolimus (rapamycin).